- Named for the smoke-like bluish haze that often envelopes the mountains, the Great Smoky Mountains National Park is the most visited national park in the United States
- Located in Chattanooga, the Tennesse Aquarium is the largest freshwater aquarium in the world
- The world’s largest fireworks display is called Thunder Over Louisville and is the opening ceremony for the Kentucky Derby Festival
- The first self-service grocery store, the Piggly Wiggly, opened in Memphis in 1917
- Located near Corbin, Kentucky, Cumberland is the only waterfall in the world to regularly display a moonbow
- Pikeville, Kentucky, leads the nation in consumption of Pepsi-Cola
- The Memphis Cotton Exchange still handles approximately one-third of the entire American cotton crop each year
- Middlesboro, Kentucky, is the only city in the U.S. built within a meteor crater